Chargers Spring 2021 Schedule
| Details | Date | Time | Opponent | Score | Location |
| April | |||||
| Box Score | Sat, 4/17/21 | 12:30 pm | @ Broncos | W 51 - 30 | Lighthouse Field |
| Box Score | Mon, 4/19/21 | 2:00 pm | Seahawks | L Forfeit | Lighthouse Field |
| May | |||||
| Box Score | Sat, 5/8/21 | 11:00 am | @ Cardinals | L 20 - 50 | |
| Box Score | Sat, 5/15/21 | 12:30 pm | @ Colts | L 13 - 38 | Lighthouse Field |
| Box Score | Sat, 5/22/21 | —:— — | @ Bills | L 12 - 54 | Lighthouse Field |
| June | |||||
| Box Score | Sat, 6/5/21 | 10:45 am | Bucs | L 46 - 42 | |
| Box Score | Sat, 6/5/21 | 12:45 pm | Steelers | L 30 - 19 | |
| Box Score | Sat, 6/12/21 | 11:00 am | Broncos | W 18 - 32 | Lighthouse Field |
