Colts Spring 2021 Schedule
| Details | Date | Time | Opponent | Score | Location |
| April | |||||
| Box Score | Sat, 4/17/21 | 11:00 am | @ Cardinals | L 33 - 53 | Lighthouse Field |
| Box Score | Sat, 4/24/21 | 12:30 pm | @ Steelers | W 32 - 26 | Lighthouse Field |
| May | |||||
| Box Score | Sat, 5/8/21 | 12:30 pm | @ Eagles | W 28 - 13 | Lighthouse Field |
| Box Score | Sat, 5/15/21 | 12:30 pm | Chargers | W 13 - 38 | Lighthouse Field |
| Box Score | Sat, 5/22/21 | 2:00 pm | PAC-9 | L 22 - 19 | Iglesia del Barrio |
| June | |||||
| Box Score | Sat, 6/5/21 | 11:45 am | @ Bills | W 38 - 26 | |
| Box Score | Sat, 6/5/21 | 1:45 pm | @ Seahawks | L 32 - 37 | |
| Box Score | Sat, 6/12/21 | 12:30 pm | Cardinals | W 25 - 41 | |
